Table 3.

Summary of FDA-Approved Topical Onychomycosis Medications

Medication	Dosing	Mycologic Cure Rate (%), Toenails	Complete Cure Rate (%), Toenails	Penetrates Nail Polish	Degrades Nail Polish	Debridement Recommended With Use	US FDA Approval
Ciclopirox lacquer	8% once daily for 48 weeks	29–36	5.5–8.5	NR	NR	Yes	Yes
Efinaconazole solution	10% once daily for 48 weeks	53.4–55.2	15.2–17.8	Yes	Yes	No	Yes
Tavaborole solution	5% once daily for 48 weeks	31.1–35.9	6.5–9.1	Yes	No	No	Yes

Abbreviations: FDA, Food and Drug Administration; NR, not reported; US, United States.