Figure 1.

Inhibitory effects of cisplatin and oxaliplatin on human Hep-2 laryngeal cancer cell growth. (a) The cells were incubated with cisplatin or oxaliplatin (5, 7.5, and 10 μM) for 48 h Cell viabilities were determined by MTT assay. (b) Cell apoptosis was determined by propidium iodide and annexin V staining. (c) The population of apoptotic cells including early- and late-apoptosis (annexin V⁺PI⁻ and annexin V⁺PI⁺, respectively), and/or necrotic cells were analyzed by flow cytometer. Data were represented as the means ± SD. ns indicates no significant difference.