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Met reduces RANKL-induced osteoclastogenesis by no cytotoxicity. (a) Chemical structure of Met. (b) The viability of cells unaffected by Met treatment at a concentration of 400 μM. (c) BMMs stimulated with specified concentrations of Met in osteoclastogenesis media (0, 200, and 400 μM), fixed, and stained with TRAP (∗p < 0.05, scar bar = 100 μm). The green arrows indicate TRAP-positive cells.
