Table 3.
Relationship between JNET classification and pathological findings, and diagnostic performance of NBI, Laser-BLI and LED-BLI
| Pathological findings | Diagnostic performance (%, 95% CI) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| JNET classification | N (%) | HP/SSL | LGD | HGD+s-SM | d-SM | Sensitivity | Specificity | PPV | NPV | Accuracy | Cronbach’s alpha | |
| NBI | Type 1 | 123 (16.2) | 111 | 9 | 3 | 0 | 84.0 (79.1-89.0) | 89.6 (87.0-92.2) | 90.2 (85.0-95.5) | 95.4 (93.8-97.1) | 94.6 (93.0-96.2) | |
| Type 2A | 479 (63.0) | 29 | 379 | 71 | 0 | 81.5 (78.0-85.0) | 66.1 (60.7-71.5) | 79.1 (75.5-82.8) | 69.4 (64.0-74.8) | 75.5 (72.5-78.6) | ||
| Type 2B | 151 (19.9) | 0 | 77 | 72 | 2 | 47.7 (39.7-55.6) | 87.0 (84.4-89.7) | 47.7 (39.7-55.6) | 87.0 (84.4-89.7) | 79.2 (76.3-82.1) | ||
| Type 3 | 7 (0.9) | 0 | 0 | 5 | 2 | 50.0 (10.0-99.0) | 99.3 (98.8-99.9) | 28.6 (-4.9-62.0) | 99.7 (99.4-100.1) | 99.1 (98.4-99.8) | ||
| Total | 760 (100) | 140 | 465 | 151 | 4 | 0.920 | ||||||
|
Laser- BLI |
Type 1 | 217 (25.1) | 200 | 17 | 0 | 0 | 81.0 (76.1-85.9) | 97.2 (96.0-98.5) | 92.2 (88.6-95.7) | 92.7 (90.7-94.7) | 92.6 (90.9-94.3) | |
| Type 2A | 512 (59.2) | 47 | 391 | 74 | 0 | 80.1 (76.6-83.7) | 67.9 (63.2-72.6) | 79.1 (75.5-82.8) | 72.5 (67.9-77.2) | 74.8 (71.9-77.7) | ||
| Type 2B | 131 (15.1) | 0 | 77 | 54 | 0 | 41.5 (33.1-50.0) | 89.5 (87.3-91.7) | 41.2 (32.8-49.7) | 89.6 (87.4-91.8) | 82.3 (79.8-84.9) | ||
| Type 3 | 5 (0.6) | 0 | 3 | 2 | 0 | N/A | 99.4 (98.9-99.9) | 0 (0.0-0.0) | 100 (100.0-100.0) | 99.4 (98.9-99.9) | ||
| Total | 865 (100) | 247 | 488 | 130 | 0 | 0.889 | ||||||
| LED-BLI | Type 1 | 195 (26.8) | 159 | 36 | 0 | 0 | 85.5 (80.4-90.5) | 93.3 (91.2-95.4) | 81.5 (76.1-87.0) | 94.7 (92.8-96.6) | 91.2 (89.1-93.3) | |
| Type 2A | 440 (60.5) | 27 | 346 | 67 | 0 | 81.2(77.5-84.9) | 69.0 (63.8-74.2) | 78.6 (74.8-82.5) | 72.1 (66.9-77.3) | 76.1 (73.0-79.2) | ||
| Type 2B | 92 (12.7) | 1 | 44 | 47 | 0 | 41.2 (32.2-50.3) | 92.8 (90.8-94.9) | 51.1 (40.9-61.3) | 89.4 (87.1-91.8) | 84.6 (82.0-87.2) | ||
| Type 3 | 0 (0) | 0 | 0 | 0 | 0 | N/A | 100 (100.0-100.0) | N/A | 100 (100.0-100.0) | 100 (100.0-100.0) | ||
| Total | 727 (100) | 186 | 426 | 114 | 0 | 0.926 | ||||||
This table shows cumulative results of the four evaluators
NBI narrow band imaging, Laser-BLI blue laser imaging, LED-BLI blue light imaging, JNET Japanese NBI expert team, SSL sessile serrated lesion, s-SM shallow submucosal, d-SM deep submucosal, PPV positive predictive value, NPV negative predictive value