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. 2022 Aug 12;47(11):1939–1944. doi: 10.1038/s41386-022-01410-5

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© The Author(s), under exclusive licence to American College of Neuropsychopharmacology 2022, Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Fig. 4 — RT retention of nicotine after use of C-cig and E-cig (A) was assessed at 25 min after inhalation of a single puff from respective ¹¹C-nicotine–containing product and expressed as percentage of total absorbed dose (TAD). Right panel (B) shows the association of brain nicotine accumulation (C_max) with RT retention after using E-cig (r_s = −0.59, p < 0.05 after correction for multiple testing). For other correlations, see Table 1.