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. 2022 Sep 19;13(9):800. doi: 10.1038/s41419-022-05189-7

Fig. 2. Low expression of SEAS1 facilitates proliferation, invasion, and inhibits apoptosis of TNBC cells.

Fig. 2

A–C CCK-8, colony formation, and EdU assay results show the proliferation rate status of control and SEAS1 silenced MDA-MB-231 and BT-549 cells. D Flow cytometry analysis shows the apoptotic rate in the control and SEAS1 knockdown MDA-MB-231 and BT-549 cells. The cells were stained with AnnexinV and PI. E Transwell assays show the migration and invasiveness of MDA-MB-231 and BT-549 cells transfected with si-NC or siSEAS1. The data represent average of three independent experiments. *P < 0.05, **P < 0.01, and ***P < 0.001. Representative data from at least 3 experiments with comparable results are shown.