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. 2021 Sep 1;9(6):1521–1555. doi: 10.1016/j.gendis.2021.08.003

Figure 5.

Figure 5

Pie-in-pie chart of CHIP as a double agent in the context to cancer. CHIP client proteins classified according to the hallmarks of cancer and its dual role as a tumor suppressor (left hand sided pie chart) and as an oncogene (right hand sided pie chart) explained.