Table 1.
ANOVA analysis of dACC glutamate and GABA measures (mean ± sem) from baseline through day 21 and after controlling for consumptions of alcohol and cigarettes (ANCOVA), where BL = baseline, D7 = abstinent day 7th, D21 = abstinent day 21st, MJ = cannabis users, HC = non-use controls.
| Time | BL | D7 | D21 | ANCOVA |
|---|---|---|---|---|
| Glu(MJ) | 7.90 ± 0.13 | 7.87 ± 0.18 | 7.98 ± 0.13 | |
| Glu(HC) | 8.47 ± 0.16 | 8.36 ± 0.11 | 8.27 ± 0.12 | |
| Time | F = 0.22, p = 0.80 | F = 0.23, p = 0.80 | ||
| Time*group | F = 0.76, p = 0.47 | F = 0.78, p = 0.47 | ||
| Groups | F = 6.86, p = 0.014 | F = 5.90, p = 0.022 | ||
| GABA(MJ) | 1.63 ± 0.05 | 1.55 ± 0.06 | 1.64 ± 0.06 | |
| GABA(HC) | 1.67 ± 0.06 | 1.72 ± 0.09 | 1.70 ± 0.06 | |
| Time | F = 0.13, p = 0.88 | F = 0.13, p = 0.88 | ||
| Time*group | F = 0.87, p = 0.42 | F = 0.85, p = 0.43 | ||
| Groups | F = 2.93, p = 0.098 | F = 2.97, p = 0.096 |
Statistically significant p<0.05 values are in bold.