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. 2022 Apr 27;9(6):1608–1623. doi: 10.1016/j.gendis.2022.04.004

Table 1.

American Joint Committee on Cancer (AJCC) TNM staging of melanoma.

T Designation Primary Tumor Thickness (mm) N Designation Regional Lymph Node M Designation Distant Metastasis
Tis n/a Nx lymph node cannot be assessed M0 no metastasis
T1 ≤1.0 N1 1 lymph node M1a skin, cutaneous, distant lymph node
T2 1.0–2.0 N2 2-3 lymph nodes M1b lung
T3 2.0–4.0 N3 4+ lymph nodes M1c other visceral sites
T4 ≥4.0 M1d central nervous system