Table 3.
Univariate and multivariate Cox regression analyses of improved clinical status.
| Variables | Univariate |
Multivariate |
||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Gender | 0.872 | |||
| Female | 0.96 (0.588–1.57) | |||
| Male | 1 | |||
| Age | 0.033 | 0.022 | ||
| ≦48 | 1.709 (1.044–2.799) | 1.837 (1.093–3.086) | ||
| ≧49 | 1 | 1 | ||
| MGFA classification | 0.723 | |||
| I + IIA | 0.889 (0.465–1.70) | |||
| IIB + III | 1 | |||
| WHO histologic type | 0.227 | |||
| A + AB | 1.428 (0.801–2.543) | |||
| B1 + B2 + B3 | 1 | |||
| Masaoka–Koga stage | 0.901 | |||
| I | 1.055 (0.455–2.444) | |||
| II | 1 | |||
| Steroids preoperatively | 0.279 | |||
| Yes | 0.736 (0.423–1.281) | |||
| No | 1 | |||
| Immunosuppressive drugs preoperatively | 0.326 | |||
| Yes | 0.702 (0.347–1.422) | |||
| No | 1 | |||
| Perioperative immunoglobin | 0.339 | |||
| Yes | 0.773 (0.457–1.31) | |||
| No | 1 | |||
| Surgical approach | 0.033 | 0.016 | ||
| Subxiphoid | 1.701 (1.044–2.773) | 1.892 (1.127–3.177) | ||
| Trans-sternal | 1 | 1 | ||
MGFA, Myasthenia Gravis Foundation of America; HR, hazard ratio; CI, confidence interval.