TABLE 2.
Differences in characteristics between COA and TCA studies at baseline.
| Characteristics | COA | TCA | p-value |
| Age (years) | 66.2 (64.8–67.6) | 64.7 (63.5–65.9) | 0.209 |
| Male (%) | 61.7 (58.5–64.8) | 64.6 (52.9–76.2) | 0.486 |
| PersAFib and (or) LSPAFib (%) | 48.3 (32.2–64.3) | 87.9 (70.0–95.8) | <0.001 |
| Hypertension (%) | 75.5 (71.0–80.1) | 67.6 (55.6–79.6) | 0.162 |
| Diabetes mellitus (%) | 19.8 (17.0–22.5) | 20.4 (10.5–30.3) | 0.729 |
| CHADS2-VASc score | 3.3 (2.9–3.6) | 2.3 (2.2–2.4) | 0.012 |
| LVEF (%) | 61.3 (59.7–62.9) | 58.5 (52.7–64.3) | 0.209 |
| Left atrial dimension (mm) | 43.4 (41.7–45.1) | 48.3 (43.9–52.8) | 0.009 |
| Prior stroke/TIA (%) | 39.8 (29.4–50.1) | 10.1 (7.2–12.9) | 0.005 |
Data are presented as means or proportions followed by the 95% confidence interval.
P-value of the meta-regression was computed using the metric “Untransformed Proportion” in a binary random-effects model using study type as covariate factor.
PersAFib, persistent atrial fibrillation; LSPAFib, longstanding persistent atrial fibrillation; LVEF, left ventricular ejection fraction; TIA, transient ischemic attack.