Table 4.
Mortality predictors among the studied cohort: logistic regression analysis.
| Variable | Multivariate | |
|---|---|---|
| OR (95% CI) | P value | |
| Age (≥55 years) | 1.675 (0.755–3.718) | 0.205 |
| Sex (male) | 0.804 (0.361–1.787) | 0.592 |
| Advanced disease stage (III–IV) | 2.245 (1.014–5.161) | 0.048 |
| Prior adjuvant chemotherapy | 0.926 (0.408–0.991) | 0.045 |
| Lymph node metastasis | 2.465 (1.078–5.638) | 0.033 |
| Liver metastasis | 2.906 (1.115–7.579) | 0.029 |
| Number of metastatic sites (≥2) | 1.554 (1.041–2.618) | 0.045 |
| Duration since diagnosis (≥30 months) | 0.590 (0.258–0.804) | 0.036 |
| Neutropenia after first cycle of FTD/TPI | 0.597 (0.269–0.954) | 0.046 |
| Number of FTD/TPI cycles | 0.832 (0.707–0.978) | 0.026 |
OR: odds ratio; CI: confidence interval; FTD/TPI: trifluridine/tipiracil.