Table 1.
Characteristics of the study cohort by outcome at baseline.
| Survived | Deceased | p-value | |
|---|---|---|---|
| Overall, n=60 (%) | 45 (75.00) | 15 (25.00) | |
| Age (years) | 55 (19) | 55 (25) | 0.6943 |
| Sex | |||
| Male (%) | 39 (86.67) | 12 (80.00) | 0.6780 |
| Female (%) | 6 (13.33) | 3 (20.00) | |
| Severity | |||
| Moderate (%) | 19 (42.22) | 2 (13.33) | 0.0420 |
| Severe(%) | 26 (57.78) | 13 (86.67) | |
| Time from admission to hospital discharge/death (days) | 11 (8) | 12.5 (12) | 0.978 |
| Time from admission to first sample (days) | 1 (1.5) | 1 (5) | 0.621 |
| Time from first sample to hospital discharge/death (days) | 9(8.5) | 8(14) | 0.461 |
| Presence of Comorbidities, n (%) | |||
| None | 23 (51.11) | 3 (20.00) | 0.035 |
| Obesity | 9 (20.00) | 9 (64.29) | 0.006 |
| Diabetes | 5 (11.11) | 2 (14.29) | 0.666 |
| High Blood Pressure | 8 (17.78) | 5 (35.71) | 0.266 |
| CKD | 1 (2.22) | 0 (0.00) | 1.000 |
| COPD | 1 (2.22) | 2 (14.29) | 0.137 |
| CVD | 0 (0.00) | 1 (7.14) | 0.237 |
| Gout | 1 (2.22) | 0 (0.00) | 1.000 |
| Other | 3 (6.67) | 0 (0.00) | 0.566 |
| Haemoglobin, white blood cell count and other biomarkers | |||
| Haemoglobin (g/dL), mean (SD) | 14.38 (1.52) | 13.19 (1.93) | 0.0176 |
| Leucocytes (109/L) | 9 (6.87) | 12.485 (8.17) | 0.2142 |
| Band neutrophils (%) | 2 (3) | 2 (2) | 0.6491 |
| Segmented neutrophils (%) | 83 (12) | 88 (7) | 0.0060 |
| Lymphocytes (%) | 10 (10) | 6 (4) | 0.0045 |
| Total neutrophils (109/L) | 7.56 (7.32) | 10.82 (8.26) | 0.2307 |
| Total lymphocytes (109/L) | 0.94 (0.77) | 0.59 (0.33) | 0.0046 |
| Platelets (count per µL) | 345000 (147000) | 274500(45000) | 0.1850 |
| CRP (mg/mL) | 61.3 (163.8) | 168.7 (122.8) | 0.1701 |
| D-dimer (µg/mL) | 0.58 (0.51) | 0.85 (1.86) | 0.1425 |
| Ferritin (µg/L) | 789.7 (679.5) | 1261.1 (838) | 0.0536 |
| Creatinine (mg/dL) | 0.7 (0.2) | 0.8 (0.48) | 0.4152 |
| PT (s) | 11.17 (0.89) | 11.57 (1.31) | 0.1627 |
| APTT (s) | 30.87 (5.15) | 32.65 (4.22) | 0.1782 |
| Sa/FiO2 | 240 (162.63) | 108.73 (35.40) | 0.0007 |
Values of continuous variables are reported as median (interquartile range), unless stated otherwise. CKD, Chronic Kidney Disease; COPD, Chronic Obstructive Pulmonary Disease; CVD, Cardiovascular disease; CRP, CReactive Protein; PT, Prothrombin Time; APTT, Activated Partial Thromboplastin Time; SaFiO2, Oxygen saturation/Fraction of inspired oxygen.