Table 2.
Zonulin, cytokines and chemokines values in serum at baseline by outcome.
| Survived | Deceased | p-value | |
|---|---|---|---|
| Overall, n=60 (%) | 45 (75.00) | 15 (25.00) | |
| Zonulin (ng/mL) | 1.0029 (0.8887) | 3.2644 (4.7096) | 0.0002 |
| Overall, n=42 (%) | 37 (88.1) | 5 (11.90) | |
| IL-1β (pg/mL) | 10 (1.5) | 11 (2) | 0.1194 |
| GCSF (pg/mL) | 11.5 (3) | 12 (3) | 0.3083 |
| IL-10 (pg/mL) | 19.5 (11) | 49.5 (54) | 0.1246 |
| IL-13 (pg/mL) | 8 (2) | 8(2) | 0.2062 |
| IL-6 (pg/mL) | 21 (38) | 55 (130) | 0.0295 |
| IL-12 (pg/mL) | 13 (3) | 15 (4) | 0.5556 |
| IL-17A (pg/mL) | 14 (2) | 14 (3) | 0.4770 |
| GMCSF (pg/mL) | 11 (2.5) | 14 (4) | 0.0059 |
| IL-15 (pg/mL) | 14 (3) | 18 (8) | 0.0456 |
| EGF (pg/mL) | 43 (64) | 25 (135) | 0.8612 |
| IL-5 (pg/mL) | 11 (1) | 12 (1.5) | 0.3165 |
| VEGF (pg/mL) | 20 (15.5) | 17 (110) | 0.6688 |
| IFN-γ (pg/mL) | 10 (3) | 11 (2) | 0.7092 |
| IFN-α (pg/mL) | 10 (1) | 11 (2) | 0.2605 |
| IL1-RA (pg/mL) | 12 (4.5) | 18 (33.5) | 0.0928 |
| TNF-α (pg/mL) | 27.5 (10) | 50.5 (44) | 0.0566 |
| IL-2 (pg/mL) | 13 (1) | 15 (2) | 0.0275 |
| IL-7 (pg/mL) | 13 (4) | 15 (3) | 0.3299 |
| IL-4 (pg/mL) | 8 (2) | 10 (2) | 0.1539 |
| IL-8 (pg/mL) | 66 (28.5) | 174 (258.5) | 0.0004 |
| IL-12p70 (pg/mL) | 9 (1) | 10 (2) | 0.1730 |
| IL-1a (pg/mL) | 14 (4) | 21 (5) | 0.0318 |
| IL-3 (pg/mL) | 8 (1) | 8 (1) | 0.1627 |
| TNF-β (pg/mL) | 10 (2) | 10 (2) | 0.9191 |
| Overall, n=42 (%) | 37 (88.1) | 5 (11.90) | – |
| RANTES (pg/mL) | 11089 (3360) | 10507 (4039.5) | 0.6000 |
| Eotaxin (pg/mL) | 98 (69) | 134 (123.5) | 0.8308 |
| MIP-1α (pg/mL) | 15.5 (5.5) | 22 (23.5) | 0.0081 |
| MIP-1β (pg/mL) | 118 (99) | 173 (589.5) | 0.2211 |
| MCP-1 (pg/mL) | 1620 (1938) | 9113 (1550) | 0.0008 |
| IP-10 (pg/mL) | 3501.5 (5094) | 6720 (4416) | 0.1563 |
Values of continuous variables are reported as median (interquartile range).