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. 2022 Sep 6;12:1000291. doi: 10.3389/fcimb.2022.1000291

Table 5.

Crude and adjusted* Cox regression of different factors for survival analysis.

Variables Crude Adjusted
HR (95% CI) p value HR (95% CI) p value
Severity
Severe 3.436 (0.759-15.566) p=0.109 4.282 (0.796-23.019) p=0.090
Moderate*
Obesity
Yes 3.923 (1.306-11.783) p=0.015 5.888 (1.646-21.068) p=0.006
No*
Haemoglobin 0.669 (0.444-1.008) p=0.055 0.770 (0.480-1.235) p=0.278
Seg Neutrophils 1.083 (0.980-1.197) p=0.118 1.215 (1.028-1.437) p=0.023
Lymphocytes 0.874 (0.748-1.020) p=0.087 0.764 (0.623-0.938) p=0.010
SaFiO 2 0.987 (0.975-0.999) p=0.032 0.986 (0.974-0.998) p=0.023
IL-6 1.010 (0.997-1.024) p=0.138 1.013 (0.997-1.029) p=0.122
GMCSF 1.975 (1.051-3.711) p=0.034 2.145 (0.889-5.115) p=0.085
IL-15 1.252 (1.032-1.518) p=0.023 1.218 (0.987-1.502) p=0.066
IL-2 3.080 (0.910-10.427) p=0.070 4.018 (1.001-16.132) p=0.050
IL-8 1.059 (0.997-1.124) p=0.061 1.080 (0.975-1.196) p=0.142
IL1a 1.026 (0.936-1.124) p=0.590 1.011(0.913-1.120) p=0.827
MIPα 1.969 (0.917-4.228) p=0.082 2.671 (0.781-9.129) p=0.117
MCP-1 1.001 (1.000-1.001) p=0.020 1.001 (0.999-1.002) p=0.110
Zonulin 1.106 (1.043-1.173) p=0.001 1.109 (1.038-1.185) p=0.002

*Adjustment for age, gender, and obesity. Obesity was adjusted for age and gender only. Zonulin values were not categorised for the analyses made herein.