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. 2022 Sep 6;9:915159. doi: 10.3389/fmed.2022.915159

Table 3.

Sensitivity analysis of included randomized controlled trials for the outcome of peak workload and 6MWD.

Outcomes Number of studies WMD (95% CI) Heterogeneity
Pheterogeneity I2, %
Peak workload Fixed effects model 5 6.89 (3.97, 9.81) 0.49 0
Exclusion of Casaburi 2004 no training 4 7.12 (4.18, 10.06) 0.64 0
Exclusion of Casaburi 2004 training 4 6.91 (3.98, 9.85) 0.34 11
Exclusion of Creutaberg 2003 4 7.01 (4.03, 9.98) 0.36 8
Exclusion of Piosn 2011 4 0.22 (−8.65, 9.09) 0.81 0
Exclusion of Sharma 2008 4 7.26 (4.28, 10.25) 0.56 0
6MWD Fixed effects model 5 16.88 (−3.27, 37.04) 0.21 31
Exclusion of Dage 2014 4 5.16 (−18.47, 28.78) 0.51 0
Exclusion of Ferreira 1998 4 21.83 (0.89, 42.76) 0.41 0
Exclusion of Pison 2011 4 20.85 (−9.63, 51.32) 0.13 47
Exclusion of Sharma 2008 4 17.36 (−3.03, 37.74) 0.13 48
Exclusion of Svartberg 2004 4 18.78 (−2.13, 39.69) 0.15 44

WMD, weighted mean difference; CI, confidence interval; 6MWD, 6–min walking distance.