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. 2022 Sep 6;13:925018. doi: 10.3389/fphar.2022.925018

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Copyright © 2022 Zhao, Dai, Li, Zhang, Guo, Ding, Hu and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Typical MS/MS product ion spectra of SRL and SRL-d₃. The experiment was performed under Manual Tune mode by a syringe infusing the standard solution of SRL and SRL-d₃ (100 ng/ml) at a rate of 5 μl/min (A). Interference of IS in blank samples spiked with IS only. The difference in chromatographic run time in (A) is due to the different gradient (B).