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. 2022 Sep 15;84:104268. doi: 10.1016/j.ebiom.2022.104268

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© 2022 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

The analysis of NMF clustering based on differentially expressed genes (DEGs) among three clusters in the meta-GEO cohort. (a) The Venn diagram showed 466 overlap DEGs among the three clusters. (b) The GO enrichment analysis of the DEGs. The gene counts of each GO term were presented in the x-axis and the statistical significance was indicated by the brightness of the column color. (c) The prognosis of patients in two DEGclusters was compared in the Kaplan-Meier curves via the Log-rank test. (d) The distribution of CTLA-4 and PD-L1 between two DEGclusters. (e) The Venn diagram and bar plot revealed the relationship between the three clusters and two Writer-Score groups. (f) The Venn diagram and bar plot revealed the relationship between the two DEGclusters and two Writer-Score groups.