TABLE 2.
Outcomes and methods | Number of SNPs | OR | 95% CI | P for association | P for Cochran’s Q test | P for MR-PRESSO global test |
IVW (fixed) | 6 | 3.05 | 1.11–8.35 | 0.030 | 0.698 | |
MR-Egger | 6 | / | / | 0.547a | ||
Maximum-likelihood | 6 | 3.12 | 1.10–8.79 | 0.032 | ||
MR-PRESSO (0 outliers) | 6 | 3.05 | 1.40–6.66 | 0.038 | 0.708 |
aP-value for the intercept of MR-Egger regression analysis.
CI, confidence interval; IVW, inverse-variance weighted; MR-PRESSO, Mendelian randomization pleiotropy residual sum and outlier; OR, odds ratio; SNP, single nucleotide polymorphism.