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. 2022 Sep 6;13:963638. doi: 10.3389/fphar.2022.963638

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Copyright © 2022 Nie, Geng, Liu, Qi, Wang, Liu and Tang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Chemical composition of CHMACS. HPLC/MS spectra of CHMACS in the (A) positive and (B) negative ion modes. (C) Distribution of chemical components of CHMACS and (D) of those with intensity >100,000. These active components were mainly derived from R. glutinosa, mulberry, raspberry, Psoralea, and other CHMs. (E) Classification of the active components of CHMACS based on their chemical properties. (F) Chemical components of CHMACS according to their intensity.