TABLE 3.
The clinical and pathological characters of DKD patients.
| Parameters | DKD1 (n = 10) | DKD2 (n = 13) | t (Z) | p-value |
|---|---|---|---|---|
| DM duration (M) | 74.60 ± 64.19 | 107.69 ± 74.73 | 1.117 | 0.276 |
| Scr (μmol/L) | 102.95 (49.55, 131.13) | 118.40 (93.40,150.40) | (0.806) | 0.420 |
| BUN (mmol/L) | 8.12 ± 2.01 | 8.83 ± 3.48 | 0.575 | 0.572 |
| UA (μmol/L) | 306.10 ± 76.38 | 352.92 ± 101.82 | 1.213 | 0.239 |
| eGFR [ml/min·1.73 m2] | 85.30 ± 36.15 | 70.77 ± 33.90 | 0.990 | 0.333 |
| FBS (mmol/L) | 5.54 (4.03, 6.25) | 6.84 (5.34, 8.90) | (1.210) | 0.226 |
| HbAc1 (%) | 7.10 (6.58, 7.70) | 7.60 (6.10.8.00) | (0.279) | 0.780 |
| CHO (mmol/L) | 4.31 ± 1.32 | 5.92 ± 1.08 | 3.221 | 0.004 |
| TG (mmol/L) | 1.95 (1.20.2.27) | 1.50 (1.37.2.30) | (0.620) | 0.535 |
| LDL (mmol/L) | 2.46 ± 1.27 | 3.88 ± 0.85 | 3.201 | 0.004 |
| VLDL (mmol/L) | 0.72 (0.45.0.84) | 0.56 (0.51.0.85) | (0.559) | 0.576 |
| HDL (mmol/L) | 1.03 ± 0.36 | 1.24 ± 0.27 | 1.616 | 0.121 |
| ALB (g/L) | 41.66 ± 2.30 | 30.68 ± 6.86 | -5.393 | 0.000 |
| ApoA1 (mmol/L) | 1.14 (1.01.1.22) | 1.30 (1.15.1.40) | (1.850) | 0.064 |
| ApoB (mmol/L) | 0.86 ± 0.27 | 1.18 ± 0.28 | 2.702 | 0.014 |
| ApoB/ApoA1 | 0.77 ± 0.24 | 0.95 ± 0.30 | 1.440 | 0.166 |
| Lipoprotein α(mmol/L) | 111.00 (46.00,253.00) | 328.50 (166.25,626.75) | (1.845) | 0.065 |
| Glomerular lesions [n (%)] | (3.052) | 0.002 | ||
| Ⅰ | 0 (0) | 0 (0) | ||
| Ⅱ | ||||
| Ⅱa | 6 (60.00%) | 1 (7.69%) | ||
| Ⅱb | 3 (30.00%) | 3 (23.08%) | ||
| Ⅲ | 1 (10.00%) | 9 (69.23%) | ||
| Ⅳ | 0 | 0 | ||
| IFTA (0/1/2/3) | 3/4/3/0 | 0/2/9/2 | (2.810) | 0.005 |
| Interstitial inflammation (0/1/2) | 4/6/0 | 1/7/5 | (2.276) | 0.023 |
| Arteriolar hyalinosis (0/1/2) | 1/6/3 | 1/4/8 | (1.344) | 0.179 |
| Arteriosclerosis (0/1/2) | 0/8/2 | 1/7/5 | (0.595) | 0.552 |
DM, diabetic metabolism; M, month; NC, normal control; Scr, serum creatinine; BUN, blood urea nitrogen; UA, uric acid; eGFR, estimate glomerular filtration rate; FBS, fasting blood sugar; CHO, cholesterol; TG, triglycerides; LDL, low-density lipoprotein; VLDL, very-low-density lipoprotein; HDL, high-density lipoprotein; ALB, albumin; ApoB, apolipoprotein B; ApoA1, apolipoprotein A1; IFTA, interstitial fibrosis and tubular atrophy.