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. 2021 Jul 24;45(4):642–653. doi: 10.1016/j.bj.2021.07.005

Fig. 1.

Fig. 1

Altered expression of OIP5-AS1 and miR-144-5p in cisplatin-induced AKI model. The mice were induced with or without cisplatin for 1 d, 3 d and 7 d. (A–C) The serum level of creatinine (A) and BUN (B). (C) The morphology of renal tissues was evaluated by HE staining assay. Scale bar = 50 μm. (D) The tubular injury score. (E and F) The mRNA level of OIP5-AS1 (E) and miR-144-5p (F) were evaluated by qRT-PCR. (G and H) The HK-2 cells were treated with or without different concentrations of cisplatin for 24 h. The mRNA expression level of OIP5-AS1 (G) and miR-144-5p (H) was evaluated by qRT-PCR. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.