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Calculated IC50 (μM) for the inhibitors at different substrate concentrations
| NF2886 | NF2883 | NF2889 | ||||
|---|---|---|---|---|---|---|
| Substrate, μM | 50 | 150 | 50 | 150 | 50 | 150 |
| IC50 | 5.17 ± 2.58 | 9.56 ± 3.29 | 0.110 ± 0.011 | 0.041 ± 0.002 | 0.37 ± 0.13 | 0.055 ± 0.007 |
Average of two independent experiments ± SD. (50 μM vs 150 μM comparison: statistical significance, p < 0.05).
