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Fig. 17. (a) The Vernier template approach to increase the complexity of a system by targeted coordinative mismatch.83 (b) The Vernier template approach as applied to linear, circular, and knotted systems in a 2 : 3 ratio.84 (c) Synthesis of granny knot (Λ,Λ)-LuIII250 by Vernier template synthesis.27.