Table 1.
The baseline characteristics of participants
| MAP group | Low MAP group (MAP <80 mm Hg) | Medium MAP group (80≤MAP<90 mm Hg) | High MAP group (90≤MAP<100 mm Hg) | Very high MAP group (MAP ≥100 mm Hg) | P value |
| Participants | 47 430 | 70 126 | 57 530 | 35 332 | |
| Age (years） | 38.30±9.74 | 39.96±11.33 | 43.17±13.21 | 49.20±14.12 | <0.001 |
| Gender | <0.001 | ||||
| Male | 14 926 (31.47%) | 37 150 (52.98%) | 38 008 (66.07%) | 25 017 (70.81%) | |
| Female | 32 504 (68.53%) | 32 976 (47.02%) | 19 522 (33.93%) | 10 315 (29.19%) | |
| BMI (Kg/m2) | 21.60±2.73 | 22.77±3.08 | 23.91±3.29 | 25.12±3.37 | <0.001 |
| SBP (mm Hg) | 100.88±7.28 | 113.80±7.63 | 125.70±8.29 | 141.09±11.76 | <0.001 |
| DBP (mm Hg) | 61.60±4.44 | 70.47±4.13 | 78.81±4.58 | 89.45±6.48 | <0.001 |
| PP (mm Hg) | 39.28±8.32 | 43.32±10.10 | 46.89±11.38 | 51.64±13.82 | <0.001 |
| MAP (mm Hg) | 74.69±3.93 | 84.92±2.85 | 94.44±2.85 | 106.66±5.62 | <0.001 |
| FPG (mmol/L) | 4.75±0.55 | 4.87±0.58 | 4.98±0.62 | 5.11±0.66 | <0.001 |
| Scr (umol/L) | 64.99±13.89 | 69.61±14.93 | 72.38±15.12 | 73.78±16.38 | <0.001 |
| TC (mmol/L) | 4.51±0.83 | 4.64±0.86 | 4.78±0.90 | 4.96±0.93 | <0.001 |
| TG (mmol/L) | 0.84 (0.61–1.17) | 1.01 (0.71–1.46) | 1.19 (0.83–1.77) | 1.41 (1.00–2.09) | <0.001 |
| HDL-C (mmol/L) | <0.001 | ||||
| Low | 6775 (14.28%) | 12 260 (17.48%) | 11 615 (20.19%) | 7884 (22.31%) | |
| Medium | 8399 (17.71%) | 12 574 (17.93%) | 10 317 (17.93%) | 6688 (18.93%) | |
| High | 10 777 (22.72%) | 13 261 (18.91%) | 9696 (16.85%) | 6172 (17.47%) | |
| Not recorded | 21 479 (45.29%) | 32 031 (45.68%) | 25 902 (45.02%) | 14 588 (41.29%) | |
| LDL-C (mmol/L) | <0.001 | ||||
| Low | 10 722 (22.61%) | 13 561 (19.34%) | 9421 (16.38%) | 5163 (14.61%) | |
| Medium | 8756 (18.46%) | 12 905 (18.40%) | 10 658 (18.53%) | 6854 (19.40%) | |
| High | 6559 (13.83%) | 11 912 (16.99%) | 11 938 (20.75%) | 9095 (25.74%) | |
| Not recorded | 21 393 (45.10%) | 31 748 (45.27%) | 25 513 (44.35%) | 14 220 (40.25%) | |
| ALT (U/L) | 14.20 (11.00–20.10) | 17.20 (12.40–25.90 | 20.00 (14.30–31.00) | 22.60 (16.00–34.00) | <0.001 |
| AST (U/L) | <0.001 | ||||
| Low | 9198 (19.39%) | 10 381 (14.80%) | 6586 (11.45%) | 3158 (8.94%) | |
| Medium | 6386 (13.46%) | 9877 (14.08%) | 8166 (14.19%) | 4794 (13.57%) | |
| High | 4126 (8.70%) | 8869 (12.65%) | 9409 (16.35%) | 7010 (19.84%) | |
| Not recorded | 27 720 (58.44%) | 40 999 (58.46%) | 33 369 (58.00%) | 20 370 (57.65%) | |
| Smoking status | <0.001 | ||||
| Current smoker | 1563 (3.30%) | 3856 (5.50%) | 3982 (6.92%) | 2576 (7.29%) | |
| Ever smoker | 339 (0.71%) | 839 (1.20%) | 861 (1.50%) | 507 (1.43%) | |
| Never smoker | 9831 (20.73%) | 15 600 (22.25%) | 13 006 (22.61%) | 6961 (19.70%) | |
| Not recorded | 35 697 (75.26%) | 49 831 (71.06%) | 39 681 (68.97%) | 25 288 (71.57%) | |
| Drinking status | <0.001 | ||||
| Current drinker | 126 (0.27%) | 345 (0.49%) | 467 (0.81%) | 391 (1.11%) | |
| Ever drinker | 1193 (2.52%) | 3040 (4.34%) | 3043 (5.29%) | 1635 (4.63%) | |
| Never drinker | 10 414 (21.96%) | 16 910 (24.11%) | 14 339 (24.92%) | 8018 (22.69%) | |
| Not recorded | 35 697 (75.26%) | 49 831 (71.06%) | 39 681 (68.97%) | 25 288 (71.57%) | |
| Family history of diabetes | <0.001 | ||||
| No | 46 324 (97.67%) | 68 599 (97.82%) | 56 411 (98.05%) | 34 753 (98.36%) | |
| Yes | 1106 (2.33%) | 1527 (2.18%) | 1119 (1.95%) | 579 (1.64%) |
Values are n (%) or mean±SD.
ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; DBP, diastolic blood pressure; FPG, fasting plasma glucose; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipid cholesterol; MAP, mean arterial pressure; PP, pulse pressure; SBP, systolic blood pressure; Scr, serum creatinine; TC, total cholesterol; TG, triglyceride.