Skip to main content
. 2022 Sep 6;10:993257. doi: 10.3389/fcell.2022.993257

FIGURE 3.

FIGURE 3

A schematic representation showing the germarium of the Drosophila ovary. Proposed mechanism of how female GSCs are protected against apoptosis through the collaborative contribution of multiple signalling pathways. Dying cells send Pvf1 as a survival signal that activates the Tie receptor in GSCs. Tie activation leads to ban microRNA upregulation that represses Foxo and p53 mediated hid activation in response to DNA damage. Created with BioRender.com.