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. 2022 Sep 20;576:61–68. doi: 10.1016/j.virol.2022.09.003

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© 2022 The Authors

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Fig. 3 — Cross-neutralization capacity of SCTV01C immunized mouse sera against Omicron subvariants. (a) Balb/c mice were intramuscularly injected with D614G monovalent vaccine or SCTV01C (1 μg/dose) twice on Day 0 and Day 21 (n = 8/group). (b) 21 days after the second shot, moue sera were used to detect NTs against Omicron PSVs. (c) C57BL/6 mice were intramuscularly injected with D614G monovalent vaccine or SCTV01C (1 μg/dose) twice with a 2-week interval (n = 8/group). (d) Two weeks after the second immunization, sera were used to detect NTs against Omicron PsVs. Data are shown as GMT mean ± SD. GMT: geometric mean titer. SD: standard deviation. NTs: neutralizing antibody tilters. Comparisons were performed by One-way ANOVA.