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. 2022 Aug 12;10(7):663–720. doi: 10.1002/ueg2.12280

TABLE 2.

Definition of grades of recommendation 29

A At least one meta‐analysis, systematic review, or RCT rated as 1++, and directly applicable to the target population; or A body of evidence consisting principally of studies rated as 1+, directly applicable to the target population, and demonstrating overall consistency of results
B A body of evidence including studies rated as 2++, directly applicable to the target population; or A body of evidence including studies rated as 2+, directly applicable to the target population and demonstrating overall consistency of results; or and demonstrating overall consistency of results; or Extrapolated evidence from studies rated as 1++ or 1+
0 Evidence level 3 or 4; or Extrapolated evidence from studies rated as 2++ or 2+
GPP Good practice points/expert consensus: Recommended best practice based on the clinical experience of the guideline development group