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. 2022 Sep 6;13:986837. doi: 10.3389/fmicb.2022.986837

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Copyright © 2022 Wang, Li, Fan, Han, Xie, Du and Peng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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B. lactis combined with L. plantarum altered the gut microbiota composition in glioma mice. (A) Comparison of α-diversity of gut microbiota including ACE, Chao1, Simpson and Shannon index between the three groups. Wilcoxon rank-sum test. (B) NMDS analysis based on binary-jaccard distance, stress = 0.1633. Bar charts of the gut microbiota composition at the (C) phylum and (F) genus-level in the three groups. (D) F/B ratio, two-way ANOVA. (E) Relative abundance of Lactobacillus in the three groups, two-way ANOVA. (G) LDA score of enriched bacterial taxa, LDA > 3.0. Mod, Model. LDA, Linear discriminant analysis. LP, Lactobacillus plantarum; BL, Bifidobacterium lactis. ^*p < 0.05. n = 9–10.