Table 2.
The results of the reviewed literatures.
| Authors | Year | Title | Study design | Intervention | Outcome | recommendation | Level of evidence |
|---|---|---|---|---|---|---|---|
| Ross DS et al. | 2016 | Diagnosis and management of hyperthyroidism and other cause of thyrotoxicosis | Evidence based guideline | Use of ATD, beta blocker | Diagnosis and management of thyrotoxicosis | Strongly recommended and directly applicable | 1a |
| Maia AL et al. | 2013 | Diagnosis and treatment of hyperthyroidism | evidence guideline | Use of ATD, beta blocker | Diagnosis and treatment of hyperthyroidism | Strongly recommended and directly applicable | 1a |
| Brandt F | 2011 | Association between overt hyperthyroidism and mortality | Review and meta-analysis | – | Increase mortality rate | Strongly recommended and directly applicable | 1a |
| Yang LB et al. | 2012 | Subclinical hyperthyroidism and the risk of cardiovascular events and all-cause mortality | Meta-analysis of cohort study | – | Mortality rate | Extrapolated evidence from other study | 1a |
| Wood CL et al. | 2020 | Randomized trial of block and replace vs dose titration thionamide | RCT | Comparison | Effect of dose titration over block replace | Recommended and applicable | 1c |
| Tagami et al. | 2012 | Short-term effects of β-adrenergic antagonists and methimazole in new-onset thyrotoxicosis caused by Graves' disease | RCT | Comparison of beta blocker and metamizole | No effect on combination treatment for thyrotoxicosis but stable cardiovascular system | Strongly recommender and applicable | 1c |
| Sadiq AM et al. | 2021 | Challenges in the Management of Thyrotoxicosis Associated with Atrial Fibrillation and Heart Failure | Case report | Propranolol, digoxin, Carbimazole, and furosemide | Management of cardiac problem due to thyrotoxicosis | Weakly recommender | 3a |
| Al Jassim A | 2018 | do patients with graves' disease need to be euthyroid prior to surgery | Cohort | Beta blocker, PTU, potassium iodide, and steroid | Development of thyroid storm | Extrapolate evidence from other study | 2a |
| Marcia Rashelle Palace | 2017 | Perioperative optimization of thyrotoxicosis patient | Review | Beta blocker, ATD, | Continuation of beta blocker postoperatively and discontinuation of ATD | Extrapolated evidence from other study | 2a |
| Azizi F et al. | 2017 | Long term ATD treatment | Systematic Review and meta-analysis | ATD | Duration of ATD | Strongly recommender& directly applicable | 1a |
| Eyob Alemayehu Gebreyohans et al. | 2019 | Normalization of TFT in thyrotoxicosis patient | Retrospective cohort | PTU, atenolol | Normalization of TFT | Extrapolate evidence from other study | 2a |
ATD; Antithyroid Drug, PTU; propylthiouracil, TFT: Thyroid function test.