Table 2.
Prevalence of familial hypercholesterolemia (FH) and severe hypercholesterolemia in Ontario, stratified by sex∗
| Groups | Number of subjects in the population | Definite FH | Probable FH | Severe hypercholesterolemia |
|---|---|---|---|---|
| Overall | 922,646 | 0.10 (0.10, 0.11) | 0.16 (0.15, 0.17) | 7.90 (7.84, 7.96) |
| Sex | ||||
| Men | 419,738 | 0.05 (0.05, 0.06) | 0.08 (0.08, 0.09) | 5.80 (5.73, 5.87) |
| Women | 502,908 | 0.15 (0.14, 0.16) | 0.22 (0.21, 0.24) | 9.66 (9.57, 9.74) |
Values indicate prevalence as a percentage, with (95% confidence interval), unless otherwise indicated.
∗
Estimation of FH and severe hypercholesterolemia incorporated adjustment for statin therapy use. This was done by multiplying low-density lipoprotein-cholesterol (LDL-C levels) for individuals with a known statin prescription in the 100 days prior to their LDL-C test by 1.43 to estimate untreated LDL-C levels.