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. 2022 Jul 26;34(2):133–147. doi: 10.4103/joco.joco_308_21

Figure 11.

Figure 11

Estimated weighted mean difference of baseline to 12-month (pictured top), and baseline to 24-month central macular thickness (μm) (pictured bottom) stratified by study design. Dashed line represents weighted mean difference. 12-month randomized controlled trial (RCT) weighted mean difference: –147.52 μm, P < 0.001. 12-month non-RCT weighted mean difference: –127.48 μm, P < 0.001. 24-month RCT weighted mean difference: –111.66 μm, P = 0.072. 24-month non-RCT weighted mean difference: –106.64 μm, P < 0.001. Values reported as crude mean difference, without adjustment for covariates. CI: Confidence interval.