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. 2022 Sep 2;22:232. doi: 10.1186/s12906-022-03707-w

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — UVB-induced wrinkle formation was attenuated by water extract of Alpinia officinarum rhizome (WEAOR) treatment. Wrinkles were analyzed using a skin replica taken from the dorsal area of the control, UVB, UVB + WEAOR 25, and UVB + WEAOR 50 mouse groups (n = 5). Representative pictures of mouse dorsal area (upper panel) and skin replica (lower panel) (A), and the number of wrinkles was counted and tabulated (B). Each data value is expressed as mean ± SD. Different letters indicate significant differences between groups (P < 0.05)