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Senile osteoporosis is a low-bone turnover disease. Aging makes the immune cells senescent. On the one hand, the senescent immune cells promote the differentiation of mesenchymal cells into adipocytes and inhibit the differentiation of mesenchymal cells into osteoblasts; further, the altered immune cells promote osteoclastogenesis. Note: Various types of immune cell image materials are from https://smart.servier.com.
