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. 2013 Sep;22(129):258–264. doi: 10.1183/09059180.00003513

Table 2. Long-term survival outcomes in medically treated chronic post-embolic pulmonary hypertension patients.

Treatment Administration First author [Ref.] Patients n NYHA-FC 6MWD m Survival %
Year 1 Year 2 Year 3 Year 5
Bosentan Orally Hughes [22] 47 II–IV 291±116 96 90 NA NA
Bosentan Orally Seyfarth [15] 12 III 319±85 100 100 NA NA
Epoprostenol i.v. Cabrol [6] 27 III–IV 265±117 73 59 41 NA
Treprostinil Subcutaneously Skoro-Sajer [7] 25 III–IV 260±111 80 80 80 53
Medical# Suntharalingam [23] 35 NA NA 77 NA 53 NA
Medical Condliffe [20] 148 II–IV 239±133 82 NA 75 55
Medical+ Simonneau [21] 275 II–IV 315 88 79 70 NA

Data are presented as mean±sd, unless otherwise stated. NYHA-FC: New York Heart Association functional class; 6MWD: 6-min walking distance; NA: not available. #: 68% received medical treatment; : 86% received medical treatment; +: 61% received medical treatment.