Table 1. Patient risk assessment.
Parameter | Stable and satisfactory | Stable and not satisfactory | Unstable and deteriorating | |||
ESC/ERS guidelines | Current case | ESC/ERS guidelines | Current case | ESC/ERS guidelines | Current case | |
Clinical RV failure | No | Yes | Yes | |||
Rate of progression | Slow | Rapid | Rapid | |||
Syncope | No | No | Yes | |||
NYHA FC | I, II | III | IV | IV | ||
6MWD m | >500# | 300–500 | <300 | 220 | ||
V ′O2peak mL·min−1·kg−1 | >15 | 12–15 | <12 | Not determined | ||
BNP/NT-proBNP | Normal/near normal | Elevated | Very elevated/increasing | Very elevated | ||
Echocardiography findings | No PE and TAPSE >2.0 cm | TAPSE 1.5–2.0 cm | PE and/or TAPSE <1.5 cm | PE and TAPSE 1.2 cm | ||
Haemodynamics | RAP <8 mmHg and CI ≥2.5–3.0 L·min−1·m−2 |
RAP 8–15 mmHg or CI 2.0–2.5 L·min−1·m−2 |
RAP 12 mmHg | RAP >15 mmHg and/or CI ≤2.0 L·min−1·m−2 | CI 1.6 L·min−1·m−2 |
ESC: European Society of Cardiology; ERS: European Respiratory Society; RV: right ventricular; NYHA: New York Heart Association; FC: functional class; 6MWD: 6-min walking distance; V′O2peak: peak oxygen uptake; BNP: brain natriuretic peptide; NT-proBNP: N-terminal pro-BNP; PE: pericardial effusion; TAPSE: tricuspid annular plane systolic excursion; RAP: right atrial pressure; CI: cardiac index. #: depending on age, height, weight, aetiology of pulmonary arterial hypertension and presence of comorbidities. Adapted from [3] with permission from the publisher.