The validation cohort
Prediction score	Sensitivity (%) (95% CI)	Specificity (%)(95% CI)	PPV (%)(95% CI)	NPV (%)(95% CI)	LR+(95% CI)	LR-(95% CI)
Low scoreof -1.50	98.0 (89.2–99.9)	22.2 (12.7–34.5)	49.5 (46.0–52.9)	93.3 (65.6–99.0)	1.26(1.10–1.45)	0.09 (0.01–0.67)
Optimal scoreof 0.03	69.4 (54.6–81.8)	71.4 (58.7–82.1)	65.4 (55.1–74.4)	75.0 (65.7–82.5)	2.43(1.58–3.74)	0.43 (0.27–0.67)
High score of 1.40	12.2 (4.63–24.08)	98.4 (91.5–99.9)	85.7 (42.6–98.0)	59.1 (56.4–61.7)	7.71(0.96–61.99)	0.89 (0.80–0.99)

95% CI, 95% confidence interval; LR-, negative likelihood ratio; LR+, positive likelihood ratio; NPV, negative predictive value; PPV, positive predictive value.