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. 2022 Aug 8;66(9):e01893-21. doi: 10.1128/aac.01893-21

FIG 4.

FIG 4

Simulated target attainment (fAUCss/MIC ≥10 for 1.0 log-kill target or ≥42 for resistance suppression target) for weight-band and fixed-dose regimens. (A) Weight-band (weight range, 40 to 50 kg) 250-mg twice-daily (BID) dose; (B) weight-band (weight range, 50 to 67 kg) 375-mg BID dose; (C) fixed-dose 375-mg BID dose; (D) weight-band (weight range, 40 to 50 kg) 500-mg once-daily (QD) dose; (E) weight-band (weight range, 50 to 67 kg) 750-mg QD dose; (F) fixed-dose 750-mg QD dose. Bottom and top solid lines in each figure represent fAUCss/MIC values ≥10 and ≥42, respectively.