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Microphotographs (×20) of endobronchial biopsies from a) healthy control, b) mildly asthmatic and c) severe asthmatic airways demonstrating increased thickness of the basement membrane (haematoxylin–eosin stain) and goblet cell (GC) hyperplasia (periodic acid–Schiff stain) as asthma severity increases. EP: epithelium; RBMt: reticular basement membrane; Ang: angiogenesis. Scale bars=50 μm.
