TABLE 1.
Demographic and Clinical Features of 231 ET Cases
| All ET Cases | ET Cases With LBs | ET Cases Without LBs | Comparison of ET Cases With LBs to ET Cases Without LBs | |
|---|---|---|---|---|
| n | 231 | 58 | 173 | NA |
| Age at death (years) | 89.0 ± 6.4 (90.0) | 88.7 ± 6.3 (89.0) | 89.1 ± 6.4 (90.0) | p = 0.76* |
| Age of action tremor onset (years) | 44.5 ± 23.1 (47.0) | 47.4 ± 23.2 (50.0) | 43.4 ± 23.1 (45.0) | p = 0.18* |
| Tremor duration (years) | 44.5 ± 22.7 (39.0) | 41.3 ± 22.2 (36.0) | 45.6 ± 22.80 (42.0) | p = 0.19* |
| Female gender | 144 (62.3) | 36 (62.1) | 108 (62.8) | p = 0.92† |
| Total tremor score | 24.0 ± 7.3 (23.8) | 24.6 ± 6.4 (24.0) | 23.8 ± 7.6 (23.5) | p = 0.67* |
| Intention tremor score | 0.3 ± 0.7 (0.0) | 0.3 ± 0.6 (0.0) | 0.4 ± 0.7 (0.0) | p = 0.37* |
| Head tremor | 147 (65.9)§ | 38 (69.1) | 109 (64.9) | p = 0.57† |
| Voice tremor | 132 (64.7)§ | 33 (66.0) | 99 (64.3) | p = 0.83† |
| Rest tremor | § | p = 0.02‡ | ||
| Absent | 93 (48.7) | 16 (33.3) | 77 (53.8) | |
| Present in 1 position | 52 (27.2) | 15 (31.3) | 37 (25.9) | |
| Present in 2 positions | 17 (8.9) | 7 (14.6) | 10 (7.0) | |
| Present in ≥3 positions | 29 (15.2) | 10 (20.8) | 19 (13.3) | |
| Rest tremor after removing all subjects with ET-ETpPD or ET- ETPD | § | p = 0.145‡ | ||
| Absent | 91 (50.8) | 14 (37.8) | 77 (54.2) | |
| Present in 1 position | 47 (26.3) | 11 (29.7) | 36 (25.4) | |
| Present in 2 positions | 17 (9.5) | 7 (18.9) | 10 (7.0) | |
| Present in ≥3 positions | 24 (13.4) | 5 (13.5) | 19 (13.4) | |
| First-degree relative with ET | 97 (42.2)§ | 24 (41.4) | 73 (42.4) | p = 0.89† |
All values are mean ± standard deviation (median) or number (percentage) unless otherwise specified.
ET, essential tremor; ET-ETpPD, essential tremor and then possible PD; ET-ETPD, essential tremor and then PD; NA, not applicable.
*
Mann-Whitney test.
†
Chi-square test.
‡
Linear-by-linear association.
§
Number of subjects <231 due to incomplete data.