TABLE 4.

Cerebellar Pathology in 58 ET Cases Stratified into 10 Categories of Lewy Pathology

Category	Location of LP	N	PC/mm	Torpedo/mm (LH&E)	Torpedo/mm (Bielschowsky)	Basket Rating
1	NSPD 1	1	2.90	0.198	0.222	2.0
2	NSPD 2	4	3.65 ± 1.03	0.045 ± 0.019 (median = 0.035)	0.070 ± 0.063 (median = 0.057)	1.88 ± 0.48 (median = 1.75)
3	NSPD 3	8	3.40 ± 0.71	0.096 ± 0.059 (median = 0.089)	0.108 ± 0.077 (median = 0.106)	2.08 ± 0.92 (median = 2.0)
4	NSPD 4	5	3.75 ± 0.90	0.075 ± 0.035 (median = 0.056)	0.103 ± 0.046 (median = 0.086)	2.20 ± 0.84 (median = 2.0)
5	NSPD5	8	4.26 ± 0.33	0.062 ± 0.037 (median = 0.043)	0.094 ± 0.056 (median = 0.074)	2.19 ± 0.59 (median = 2.0)
6	NSPD 6	7	3.96 ± 1.14	0.091 ± 0.035 (median = 0.088)	0.128 ± 0.050 (median = 0.123)	1.86 ± 0.69 (median = 1.5)
7	Amygdala predominant	10	3.97 ± 1.53	0.099 ± 0.058 (median = 0.103)	0.118 ± 0.057 (median = 0.109)	2.30 ± 0.54 (median = 2.0)
8	LC only	2	4.25 ± 0.48	0.025 ± 0.009 (median = 0.025)	0.057 ± 0.053 (median = 0.057)	1.75 ± 0.35 (median = 1.75)
9	≥2 regions not fitting Braak staging	11	4.14 ± 1.05	0.064 ± 0.052 (median = 0.047)	0.073 ± 0.051 (median = 0.064)	1.91 ± 0.58 (median = 2.0)
10	OB only	2	3.34 ± 0.43	0.067 ± 0.016 (median = 0.067)	0.063 ± 0.0001 (median = 0.063)	2.0 ± 0.0 (median = 2.0)
p value			0.77*	0.08†	0.21†	0.89†

All values are mean ± standard deviation or number (percentage) unless otherwise specified.

LC, locus coeruleus; LH&E, Luxol fast blue hematoxylin & eosin; LP, Lewy pathology; NSPD, neuropathological stage of Parkinson disease; OB, olfactory bulb; PC, Purkinje cell.

^*Analysis of variance.

^†Kruskal-Wallis test.