TABLE 4.

Risk factors associated with recurrent venous thromboembolism (VTE) and anticoagulant-related bleeding [2, 12, 46, 50–53]

Recurrent VTE	Serious or fatal bleeding	Both recurrent VTE and serious bleeding
Initial unprovoked VTE	Low platelet count	Increased age
Initial proximal DVT or PE	Previous bleeding	Cancer
Thrombophilia	Recent major bleeding	Immobilisation
Residual proximal thrombosis	Previous stroke	Recent surgery (transient)
Male sex	Hepatic failure	Severe renal impairment
Elevated D-dimer concentrations when not receiving anticoagulation Pregnancy Anticoagulation lasting<3 months	Diabetes Abnormal prothrombin time Thrombocytopenia Poor anticoagulant control Comorbidity Anaemia

DVT: deep vein thrombosis; PE: pulmonary embolism.