TABLE 2.
Estimated α1-antitrypsin (AAT) deficiency PI*S and PI*Z gene frequency in 1203 patients with chronic obstructive pulmonary disease referred to targeted screening within the central Eastern European Alpha-1 Antitrypsin Network programme: 2013 to June 2014
| Estimated AAT genotype frequency | ||
| PI*S | PI*Z | |
| Bulgaria | 20.3 (−2.4–43) | |
| Lithuania | 47.6 (−16.8–112) | |
| Poland | 19.2 (11.3–27.2) | 47.2 (34.9–59.5) |
| Romania | 19.6 (9.7–29.4) | 14.4 (5.9–22.8) |
| Slovakia | 13.1 (0.3–25.8) | 13.1 (0.3–25.8) |
| Mean | 17.9 (11.6–24.1) | 30.6 (22.5–38.7) |
Data are presented as frequency (95% CI). Frequency was calculated as 1/Hardy–Weinberg. Data from [18].