Table 4:
Number of CPIP Components at 12 Months CGA
| Cohort | Number of Components | N (%) infants surviving without CPIP at 12 months CGA | N (%) infants without CPIP in survivors at 12 months CGA | ||||
|---|---|---|---|---|---|---|---|
| Placebo | rhCC10 | P-value | Placebo | rhCC10 | P-value | ||
| Cohort 1 | N | 22 | 22 | 22 | 20 | ||
| None | 1 (5) | 1 (5) | >0.9 | 1 (5) | 1 (5) | >0.9 | |
| ≤1 component | 5 (23) | 3 (14) | 0.4 | 5 (23) | 3 (15) | 0.5 | |
| ≤2 components | 13 (59) | 7 (32) | 0.07 | 13 (59) | 7 (35) | 0.1 | |
| ≤3 components | 21 (95) | 13 (59) | 0.004 | 21 (95) | 13 (65) | 0.01 | |
| Cohort 2 | N | 21 | 23 | 19 | 18 | ||
| None | 3 (14) | 3 (13) | 0.9 | 3 (16) | 3 (17) | 0.9 | |
| ≤1 component | 5 (24) | 6 (26) | 0.9 | 5 (24) | 6 (33) | 0.6 | |
| ≤2 components | 8 (38) | 7 (30) | 0.6 | 8 (42) | 7 (39) | 0.8 | |
| ≤3 components | 13 (62) | 10 (43) | 0.2 | 13 (68) | 10 (56) | 0.4 | |
a:
Imputed worst-case scenario for missing data.
b:
No imputation for missing data; denominators reflect numbers of patients for whom data were collected at this time point
CPIP – chronic pulmonary insufficiency of the prematurity