TABLE 2.

Considerations in the multidisciplinary decision about locally definitive treatment

Surgery	Radiotherapy	Combined
Adequate functional status	Multilevel or bulky N2	Local tumour control is very important
Bulky, necrotic tumours with possible complications	(Small) tumours with multiple mediastinal lymph node involvement	Locally invasive tumours with slim possible resection margins (e.g. superior sulcus tumours)
Multiple nodules in the same lobe	Reasonable dose affections of lung and heart
No pneumonectomy necessary	PD-L1 inhibition possible

PD-L1: programmed death ligand 1.