TABLE 2.

Suggested minimal clinically important difference (MCID) for cardiopulmonary exercise testing outcomes

Protocol and measure	MCID
Symptom limited incremental exercise testing	0.04±0.01 L·min−1
V'O2	4±1 W
Work rate	>0.14 L or >4.5% predicted
Inspiratory capacity	≥2 points
Dyspnoea score on modified Borg scale (10 points)	≥10–20 mm
Dyspnoea score on VAS (100 mm)
Constant work rate exercise testing
Endurance time	>100 s or change >33% from baseline

Data refer to measurements at peak exercise. V'_O2: oxygen uptake; VAS: visual analogue scale.