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. 2022 Sep 6;13:933792. doi: 10.3389/fphys.2022.933792

TABLE 1.

Physiological characteristics.

N Age Body mass Height BMI Pmax 2-leg VO2max RER rest RER max Pmax VO2max
[years] [kg] [cm] [kg m−2] [Watt] [mL O2 min-1] [Watt] [mL O2 min-1]
2-leg 2-leg 2-leg 2-leg 1-leg 1-leg
All 27 26.8 ± 5.7 77.9 ± 10.4 181.6 ± 6.8 23.6 ± 3.1 318.4 ± 57.7 4,142.4 ± 697.8 0.74 ± 0.05 1.08 ± 0.05 189.6 ± 43.6 3,438.2 ± 646.9
unfit 9 24.8 ± 5.1 74.8 ± 11.7 179.4 ± 7.5 23.3 ± 4.2 266.7 ± 33.9 3,563.8 ± 449.1 0.77 ± 0.06 1.10 ± 0.06 168.3 ± 24.9 3,128.3 ± 530.7
Fit 18 27.7 ± 5.9 79.3 ± 9.8 182.6 ± 5.9 23.8 ± 2.5 342.9 ± 50.9 4,416.4 ± 632.2 0.71 ± 0.08 1.07 ± 0.08 200.3 ± 47.5 3,593.1 ± 656.8
p fitness 0.291 0.479 0.322 0.907 0.002 0.003 0.078 0.375 0.098 0.082
ACE-DD 14 25.4 ± 5.2 75.8 ± 10.1 181.9 ± 7.9 22.9 ± 2.6 305.7 ± 55.8 4,126.5 ± 761.8 0.76 ± 0.07 1.09 ± 0.07 189.6 ± 40.8 3,423.8 ± 673.9
ACE-ID/II 13 28.6 ± 6.1 80.3 ± 10.8 181.5 ± 5.8 24.4 ± 3.6 328.5 ± 63.1 4,136.9 ± 797.8 0.72 ± 0.07 1.07 ± 0.07 187.3 ± 50.1 3,450.2 ± 695.9
p genotype 0.437 0.326 0.855 0.319 0.462 0.912 0.366 0.609 0.875 0.907
p genotype x fitness 0.399 0.636 0.136 0.709 0.364 0.172 0.519 0.877 0.281 0.219

Mean ± SD for the anthropometric and physiological characteristics of the studied 27 subjects as assessed at rest, during one-legged cycling exercise in the morning after an over-night fast, and two-legged cycling exercise on an ergometer. Bold values indicate effects which were deemed significant at p < 0.05. ANOVA for the effects of the ACE I-allele (i.e., genotype) × aerobic fitness (fitness) with post-hoc test of least significant difference.