. 2022 Sep 6;13:933792. doi: 10.3389/fphys.2022.933792

TABLE 2.

Metabolic characteristics.

	n	Glucose		Total cholesterol	Low density lipoprotein	Triacylglycerol	Ketones	[mM]	High density lipoprotein	Muscle glycogen	RER	[mM]		[mg mg⁻¹]
		[mM]		[mM]	Low density lipoprotein	[mM]	Ketones	[mM]	High density lipoprotein	[mM]	RER	[mM]		[mg mg⁻¹]
		pre	post	pre	post	pre	post	pre	post	pre	post	pre	post	pre	post	pre	max
all	27	4.12 ± 0.62	4.86 ± 1.20	3.79 ± 0.57	3.93 ± 0.73	2.46 ± 0.52	2.47 ± 0.78	1.00 ± 0.62	0.90 ± 0.57	0.58 ± 0.26	0.53 ± 0.21	0.96 ± 0.31	1.16 ± 0.42	0.078 ± 0.052	0.032 ± 0.021	0.81 ± 0.16	0.91 ± 0.05
p exercise		0.016		0.546		0.982		0.362		0.160		0.126		<0.001		<0.001
unfit	9	4.11 ± 0.81	4.76 ± 1.23	3.49 ± 0.27	3.55 ± 0.33	2.34 ± 0.30	2.29 ± 0.27	1.00 ± 0.69	0.99 ± 0.75	0.55 ± 0.24	0.50 ± 0.15	0.95 ± 0.30	1.03 ± 0.30	0.091 ± 0.066	0.033 ± 0.012	0.72 ± 0.03	0.88 ± 0.03
fit	18	4.17 ± 0.51	4.86 ± 1.15	3.98 ± 0.68	4.18 ± 0.85	2.53 ± 0.64	2.60 ± 0.98	0.95 ± 0.51	0.85 ± 0.38	0.62 ± 0.25	0.57 ± 0.30	0.97 ± 0.30	1.22 ± 0.42	0.075 ± 0.042	0.033 ± 0.025	0.86 ± 0.17	0.93 ± 0.08
p fitness (pre)		0.867		0.039		0.599		0.969		0.901		0.457		0.452		0.025
p genotype (pre)		0.681		0.669		0.941		0.418		0.129		0.094		0.450		0.653
p fitness		0.452		0.003		0.260		0.556 ^a		0.901		0.418 ^a		0.472		0.006
p fitness x exercise		0.576		0.678		0.627		0.381		0.370		0.457		0.489		0.130
ACE-DD	14	4.17 ± 0.79	5.27 ± 1.23	3.76 ± 0.67	3.89 ± 0.60	2.44 ± 0.64	2.43 ± 0.75	0.84 ± 0.41	0.83 ± 0.37	0.51 ± 0.30	0.46 ± 0.19	1.05 ± 0.41	1.18 ± 0.52	0.086 ± 0.060	0.033 ± 0.011	0.77 ± 0.11	0.88 ± 0.07
ACE-ID/II	13	4.07 ± 0.50	4.30 ± 0.65	3.82 ± 0.54	3.96 ± 0.87	2.47 ± 0.47	2.50 ± 0.79	1.15 ± 0.72	0.96 ± 0.69	0.65 ± 0.18	0.59 ± 0.22	0.88 ± 0.18	1.14 ± 0.38	0.070 ± 0.043	0.031 ± 0.025	0.84 ± 0.14	0.93 ± 0.04
p genotype		0.020		0.519		0.811		0.820 ^a		0.129		0.368 ^a		0.399		0.284
p genotype x exercise		0.060		0.911		0.741		0.765		0.610		0.758		0.565		0.804
p genotype x fitness		0.902		0.948		0.981		0.056		0.459		0.551		0.429		0.993
p genotype x fitness x exercise		0.924		0.897		0.793		0.792		0.441		0.859		0.646		0.667

Mean ± SD for muscle glycogen and assessed metabolic characteristics in whole blood of the studied 27 subjects as assessed before and after exhaustive one-legged cycling exercise in the morning after an over-night fast. Bold values indicate effects which were deemed significant at p < 0.05. Repeated ANOVA for the effects of exercise x ACE I-allele (i.e., genotype) x aerobic fitness (fitness) with post-hoc test of least significant difference.

Kruskall Wallis Test.