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. 2022 Sep 6;13:933792. doi: 10.3389/fphys.2022.933792

TABLE 3.

Muscle characteristics.

n MCSA type I MCSA type II type I area capillary density capillary to-fiber ratio COX4I1
[μm2] [μm2] [%] [mm−2] [/28S rRNA]
all 27 5,598.3 ± 2023.9 6,935.6 ± 2,713.9 36.6 ± 10.4 290.3 ± 41.6 2.22 ± 0.62 11.6 ± 16.1
unfit 9 4,424.6 ± 916.5 5,709.7 ± 1800.9 34.5 ± 11.1 283.7 ± 46.5 1.95 ± 0.54 5.2 ± 4.2
fit 18 6,451.9 ± 2,126.4 7,827.1 ± 2,926.6 38.2 ± 9.8 293.4 ± 39.9 2.34 ± 0.64 16.8 ± 21.2
p fitness 0.006 0.086 0.039 0.945 0.305 0.023
ACE-DD 4,863.0 ± 1,303.6 5,704.7 ± 1891.0 38.0 ± 7.1 281.4 ± 40.0 1.99 ± 0.49 10.0 ± 19.1
ACE-ID/II 6,415.4 ± 2,310.1 8,303.2 ± 2,629.9 35.2 ± 14.1 299.1 ± 42.2 2.44 ± 0.65 13.8 ± 11.5
p genotype 0.079 0.019 0.340 0.121 0.094 0.094
fitness x genotype 0.125 0.463 0.402 0.109 0.642 0.374

Mean ± SD for selected characteristics of the studied 27 subjects in vastus lateralis muscle before one-legged exercise and glycogen concentration with exercise. Bold values indicate effects which were deemed significant at p < 0.05. ANOVA for the effects of ACE I-allele (i.e., genotype) x aerobic fitness (fitness) with post-hoc test of least significant difference.