Skip to main content
. 2022 Sep 20;7:108. doi: 10.1038/s41541-022-00535-4

Table 1.

KSHV antigens that might become the basis for effective KSHV vaccines.

Common name Gene Function Reference
Structural proteins gB ORF8 Glycoprotein, cell fusion 125
gH ORF22 Glycoprotein, binds ephrin receptors 75
gL ORF47 Glycoprotein, binds ephrin receptors 75
K8.1 ORFK8.1 Glycoprotein, binds heparan sulfate 126
KSHV complement-binding protein (KCP) ORF4 Glycoprotein, binds heparan sulfate and complement 127
gM ORF39 Glycoprotein, cell fusion 77
gN ORF53 Glycoprotein, cell fusion 77
ORF27 ORF27 Glycoprotein 128
ORF28 ORF28 Glycoprotein 129
ORF68 ORF68 Glycoprotein 130
Non-structural proteins Latency-associated nuclear antigen 1 (LANA1) ORF73 Latent genome maintenance 131
K1 ORFK1 Signaling glycoprotein 132
Viral Interleukin 6 (vlL6) vlL6 Homolog to human IL6 133
Viral G protein-coupled receptor (vGPCR) ORF74 Signaling GPCR 134